iPSC therapy|Article Discussion|Forum|SNES HUB

There are three areas of research and the influence they had on the generation of iPSCs. Firstly, the somatic cell nuclear transfer (SCNT) provided the possibility of differentiated cells retain the same genetic information as early embryonic cells; Then, the development of techniques allowed researchers to derive, culture, and study pluripotent cell lines; Lastly, the observation that transcription factors are key determinants of cell fate whose enforced expression can switch one mature cell type into another let iPSCs technology become true.

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